Study of [F 18]HX4 Positron Emission Tomography (PET) as a Tool to Detect Hypoxia in Tumors
Status:
Completed
Trial end date:
2012-02-01
Target enrollment:
Participant gender:
Summary
This pilot phase II study is designed as a test and retest study to investigate [F 18]HX4 as
a reliable non-invasive PET imaging marker for detection of tumor hypoxia regions and to
establish a threshold for [F 18]HX4 uptake in the tumor. The study will evaluate the
relationship between hypoxia biomarkers (HIF1α and CA-IX) by immunohistochemistry (IHC) and
tumor uptake of [F 18]HX4 by PET imaging.